Nefiracetam
$74.50 – $725.00
Nefiracetam is an organic oxygen compound and organic nitrogen compound. It is derived from alpha-amino acids.
Description
Product Information:
Name: Nefiracetam
CAS No.: 77191-36-7
Molecular Formula: C14H18N2O2
Molecular Weight: 246.3
Appearance:White crystal powder
Background
Alzheimer’s dementia (Alzheimer Demenz) or also known as Alzheimer’s type senile dementia, was first described by Alosis Alzheimer in 1907, and later named Alzheimer’s disease (Alzheimer’s disease, AD) after his surname. Alzheimer observed a 51-year-old woman in the psychiatric hospital in Frankfurt. She was suspicious, had memory impairment, could not find the way back to her home, and her language was abnormal, including naming, missed words and hearing comprehension, but her gait There was no obvious abnormality in the mutual aid movement and tendon reflex. The woman’s condition gradually deteriorated and she died 4 and a half years after admission. Pathological anatomy found that the brain was significantly atrophy, the cortical cells disappeared under the microscope, neurofibrillarydege Chemicalbooknerative changes in many neurons, a large number of so-called miliary lesions, namely senile plaques (senileplaques) all over the cortex. The clinical and pathological characteristics reported by Alzheimer are still considered to be the characteristics of the disease. With the aging of the world’s population, Alzheimer’s disease (AD) suffers more and more. It is the fourth “killer” after cardiovascular disease, cancer and stroke. Neurons in the brain of AD patients degenerate progressively, and neurofibrillary tangles are disordered, leading to memory loss, language difficulties, behavioral disorders, and eventually death. Although the pathological mechanism of the disease is not yet fully understood, many drug treatment options have been explored from the known pathophysiological changes of AD. One is for the defects of cholinergic function in AD; the other is for the defects of non-cholinergic nerve conduction in AD, such as peroxidation damage and inflammatory changes of free radicals.
What is Nefiracetam?
Nefiracetam is an organic oxygen compound and organic nitrogen compound. It is derived from alpha-amino acids.
Nefiracetam is a nootropic drug in the racetam family. Preliminary studies have shown that it may have certain anti-dementia properties in rats.
Benefits
The cytoprotective effect of nefiracetam is mediated by the enhancement of GABAergic, cholinergic and monoaminergic neuronal systems. Preliminary studies have shown that it can improve the indifference and motivation of patients after stroke. It may also exhibit anti-amnestic effects on Alzheimer’s disease and cerebrovascular dementia. In addition, studies on animal models have shown that it has anti-amnestic effects on a variety of memory impairment substances, including: ethanol, chlordiazepoxide, scopolamine, bicuculline, bitter toxin and cycloheximide.
Application
Nefiracetam is used to treat cerebrovascular diseases. It can enhance cognitive ability and prevent learning and memory damage by acting on the cerebral cortex. It does not have the characteristics of muscarinic receptor agonists and antagonists, nor does it inhibit the activity of acetylcholinease, so it is anti-forgetting and enhancing The effect of memory is to increase the release of acetylcholine in the cerebral cortex.
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