Sunifiram
$59.00 – $1,049.00
Sunifiram, a new and effective nootropic. Sunifiram is a kind of Ampakine, which is a class of compounds used for everything from improving attention span, improving alertness, and even extending memory life to improving one’s IQ.
Description
Product Information:
Name: Sunifiram
CAS No.: 314728-85-3
Molecular Formula: C14H18N2O2
Molecular Weight: 246.3
Appearance:white or off-white powder
What is Sunifiram?
Sunifiram (development code DM-235) is an experimental drug that has anti-amnestic effects in animal studies and is significantly more effective than piracetam. Sunifiram is a simplified molecular version of unifiram (DM-232). Another analog is sapunifiram (MN-19). As of 2016, sunifiram has not been toxicologically tested, nor has it undergone any human clinical trials, and has not been approved for use anywhere in the world.
Pharmacology
The mechanism of sunifiram is unknown. Sunifiram and unifiram have been tested at a wide range of sites, including the most important receptors, ion channels, and transporters, but they have no affinity for any site. They especially do not bind to glutamate, GABA, serotonin, dopamine, adrenergic, histamine, acetylcholine, or opioid receptors at concentrations up to 1 μM. In addition, these drugs were tested on recombinant AMPA receptors and did not show receptor enhancement, indicating that they do not act as positive allosteric modulators of AMPA receptors. However, they were able to prevent amnesia caused by the AMPA receptor antagonist NBQX in the passive avoidance test, which suggests that indirect/downstream AMPA receptor activation may be related to their memory enhancement effects. According to reports, sunifiram stimulates the CaMKII and PKCα pathways, and this effect depends on the activation of the NMDA receptor glycine site.
Sunifiram and other nootropics such as Piracetam, Levetiracetam, and Aniracetam can combat barbiturates (such as pentobarbital), diazepam, and certain other drugs in human red blood cells in vitro Inhibition of glucose transport (for Sunifiram, Ki = 26.0 uM), and this effect has been found to be related to their effectiveness in reversing scopolamine-induced memory deficits in mice. However, this effect is considered unlikely to represent the main mechanism of action of sunifiram.
Application
Sunifiram is one of the newest nootropics on the market to the family of smart drugs. It increases one’s attention span, decision-making, and learning abilities. Although its effect is believed to be much like Piracetam, the structure is similar, it is more effective.
It is being researched as a memory enhancer, potentially treating Alzheimer’s patients. It provides a wide variety of benefits including; increased attention span, improved focus, and increased learning potential. It has become very popular since its release, as the benefits are high and the side effects are low.
Boiling point: 442.0±38.0°C(Predicted)
Density: 1.154±0.06g/cm3(20ºC760Torr)
Storage conditions: Sealed in dry, 2-8°C
Solubility H2O: soluble24mg/mL
Form: solid
Acidity coefficient (pKa): 0.08±0.70 (Predicted)
Color: white
Statement:
All products on our website are only for Research and Development, not for other use.
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